Landmarks in Biochemistry Symposium 2025
June 5-6 | Rio de Janeiro, Brazil

About the Event
The Landmarks in Biochemistry Symposium is an event conceived by the Institute of Medical Biochemistry Leopoldo de Meis (IBqM), and celebrated its 10th anniversary in 2023. In 2013, it brought three renowned figures in biochemistry to Brazil, including the 2002 Nobel Prize winner in Chemistry, Kurt Wüthrich, who revolutionized the field of two-dimensional Nuclear Magnetic Resonance studies.
This event is highly significant for researchers and students of the Graduate Program in Biological Chemistry (PPGQB), as well as for undergraduate students and faculty members from other UFRJ units and higher education institutions in Rio de Janeiro. The symposium provides learning opportunities, access to high-level lectures, and collaboration with internationally renowned researchers. Furthermore, it fosters exchanges between researchers and students, strengthening academic and professional training.
This edition of the event is also a tribute to Prof. Mario Alberto Cardoso da Silva Neto, the visionary behind Landmarks in Biochemistry, a passionate scientist and former Director of IBqM, who passed away in 2017. Landmarks in Biochemistry stands out for its multidisciplinary nature, covering various fields such as the structure and function of essential biomolecules, development and metabolism, cellular and pathogen-host interactions, nanotechnology, genomics, proteomics, and bioinformatics. These areas are highly relevant to the projects developed at IBqM, which address major 21st-century health challenges, including cancer, metabolic disorders, and neurodegenerative diseases.
Talks & Speakers
For this 2025 edition, the symposium will focus on aging, featuring distinguished researchers in their respective fields. This will further strengthen academic training, promote the internationalization of IBqM’s research, and contribute to scientific advancements in biochemistry and related fields.

Diana Jurk
Mayo Clinic, US

Evandro de Souza
UNICAMP, BR

Fernanda De Felice
Queen’s University, CA

Flavia Gomes
UFRJ, BR

João Passos
Mayo Clinic, US

Luan Diniz
UFRJ, BR

Marcelo Mori
UNICAMP, BR

Nadja Souza Pinto
Queen’s University, CA

Patricia Bozza
Fiocruz, BR

Yraima Cordeiro
UFRJ, BR
Venue

Leopoldo de Meis Auditorium (CCS/UFRJ)
373 Carlos Chagas Filho Avenue – Hall L
Rio de Janeiro – RJ, Brazil
Program
Day 1 – Thursday, June 5
9h00 – 9h30
Opening
Robson Monteiro | Director, IBqM
Lina Zingali | Deputy Dean, CCS
Representative from the Rector’s Office
Representative from the Organizing Committee
9h30 – 10h20
Opening Conference – Mitochondria and cell senescence: a matter of life and death
João Passos | Mayo Clinic, USA
10h20 – 10h40
Coffee Break
10h40 – 11h40
IBqM Early Career Researcher Session
Danielle Cozachenco – Control of microglial protein synthesis in Alzheimer’s disease
Bruna Mendonça – Molecular signaling of nuclear XIAP in breast cancer: putative regulatory nodes with implications in prognosis and drug resistance
Ana Beatriz Nuno – In gut we trust: How the mosquitos’ intestine shapes zika transmission
11h40 – 12h10
Is cellular senescence relevant for galactosemia?
Claudio Masuda | Federal University of Rio de Janeiro, Brazil
12h10 – 14h
Lunch Break
14h – 14h30
Genetic and phamacological manipulation of astrocytes in aging and aging-associated conditions
Flavia Gomes | Federal University of Rio de Janeiro, Brazil
14h30 – 15h
Prion protein condensates in health and disease: functional assemblies or pathologica
Yraima Cordeiro | Federal University of Rio de Janeiro, Brazil
15h – 15h30
Neural control of systemic stress responses and longevity in C. elegans
Evandro de Souza | University of São Paulo, Brazil
15h30 - 16h
Mitochondrial DNA damage response in aging and in DNA repair diseases
Nadja Souza Pinto | University of São Paulo, Brazil
16h30 – 17h
Meet the Expert Session
João Passos and Diana Jurk | Mayo Clinic, USA
Day 2 – Friday, June 6
9h – 9h30
Physical exercise and blood-based biomarkers in Alzheimer’s disease
Fernanda De Felice | Federal University of Rio de Janeiro, Brazil
9h30 – 10h
An adipocentric view of metabolic dysfunction, senescence, and aging
Marcelo Mori | University of Campinas, Brazil
10h – 10h30
Immunometabolic reprogramming in host-pathogen interactions: mechanisms and consequences
Patricia Bozza | Oswaldo Cruz Foundation, Brazil
10h30 – 10h40
Coffee Break
10h40 – 11h10
Astrocyte mitochondrial dysfunction in the aging brain
Luan Diniz | Federal University of Rio de Janeiro, Brazil
11h10 – 12h
Closing Conference – Unravelling the role of lipid accumulation in cell senescence: implications for healthy aging
Diana Jurk | Mayo Clinic, USA
12h – 14h
Adjourn and Cocktail Reception
Robson Monteiro | Director, IBqM
Scientific Committee

Claudio Masuda
UFRJ, BR

Carla Polycarpo
UFRJ, BR

Mychael Lourenco
UFRJ, BR

Pedro Oliveira
UFRJ, BR

Robson Monteiro
UFRJ, BR
Support




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