Welcome to the
Lourenco Laboratory
About Us
Our research focuses on the understanding of molecular mechanisms of neurological diseases, with emphasis on Alzheimer’s disease and depression. Our long-term goal is to leverage our findings to promote translational advances in the development of new therapies and biomarkers for neurological disease. Our main goal is to understand the molecular mechanisms driving cognitive decline and mood impairments in neurological disease
Recent Publications
Neuroscience
Effects of Gestational Exercise on Nociception, BDNF, and Irisin Levels in an Animal Model of ADHD
Translational Psychiatry
Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans
Trends in Endocrinology & Metabolism
Irisin limits amyloid-β buildup in Alzheimer’s disease
In the News
Dr. Mychael interviewed by Casa Firjan on healthy habits for a better future
(In Portuguese) https://www.youtube.com/watch?v=sdDWa0p8BOM
Column highlights Dr. Mychael’s article
(In Portuguese) Link: https://ge.globo.com/eu-atleta/nutricao/post/2024/10/14/obesidade-prejudica-o-cerebro-veja-riscos-e-como-se-alimentar.ghtml
News in O Globo about Dr. Mychael’s research
(In Portuguese) Link: https://oglobo.globo.com/saude/noticia/2024/09/04/alzheimer-cientistas-brasileiros-identificam-substancia-que-ajuda-a-fixar-a-memoria-entenda.ghtml
Affiliations
